Author

Gopuraja Dharmalingam

Observed name: Dharmalingam, Gopuraja

Institutions: Eli Lilly (United States), Imperial College London

Observed institutions: University of Salerno, Eli Lilly (United States), Eli Lilly (United Kingdom), Institute for Complex Systems, Telethon Institute Of Genetics And Medicine, MRC London Institute of Medical Sciences, Imperial College London, University of Naples Federico II, Medical Research Council

OpenAlex ID: A5111665530

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

2013 · Juan Carlos Acosta, Ana Banito, et al. · Nature Cell Biology · 2,336

mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

2015 · Nicolás Herranz, Suchira Gallage, et al. · Nature Cell Biology · 796

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Cardiac glycosides are broad-spectrum senolytics

2019 · Ana Guerrero, Nicolás Herranz, et al. · Nature Metabolism · 366

PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells

2018 · Athena Georgilis, Sabrina Klotz, et al. · Cancer Cell · 234

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Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation

2018 · Sergi Cuartero, Felix D. Weiss, et al. · Nature Immunology · 216

Continuous Histone Replacement by Hira Is Essential for Normal Transcriptional Regulation and De Novo DNA Methylation during Mouse Oogenesis

2015 · Buhe Nashun, Peter W.S. Hill, et al. · Molecular Cell · 139

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Genome-wide identification of Ikaros targets elucidates its contribution to mouse B-cell lineage specification and pre-B–cell differentiation

2013 · Isabel Ferreirós-Vidal, Thomas Carroll, et al. · Blood · 129

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The Aurora B Kinase and the Polycomb Protein Ring1B Combine to Regulate Active Promoters in Quiescent Lymphocytes

2013 · Alberto Frangini, Marcela Sjöberg, et al. · Molecular Cell · 128

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Transcriptional gene network inference from a massive dataset elucidates transcriptome organization and gene function

2011 · Vincenzo Belcastro, Velia Siciliano, et al. · Nucleic Acids Research · 112

Coupling shRNA screens with single-cell RNA-seq identifies a dual role for mTOR in reprogramming-induced senescence

2017 · Marieke Aarts, Athena Georgilis, et al. · Genes & Development · 64

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COPI vesicle formation and N-myristoylation are targetable vulnerabilities of senescent cells

2023 · Domhnall McHugh, Bin Sun, et al. · Nature Cell Biology · 63

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microRNA-mediated regulation of mTOR complex components facilitates discrimination between activation and anergy in CD4 T cells

2014 · Antoine Marcais, Rory Blevins, et al. · The Journal of Experimental Medicine · 61

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HOCTAR database: A unique resource for microRNA target prediction

2011 · Vincenzo Alessandro Gennarino, Marco Sardiello, et al. · Gene · 57

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The ADAMTS18 gene is responsible for autosomal recessive early onset severe retinal dystrophy

2013 · Ivana Peluso, Ivan Conte, et al. · Orphanet Journal of Rare Diseases · 47

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Neuronal genes deregulated in Cornelia de Lange Syndrome respond to removal and re-expression of cohesin

2021 · Felix D. Weiss, Lesly Calderon, et al. · Nature Communications · 46

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Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK4a regulation

2013 · Nadine Martin, Nikolay Popov, et al. · The EMBO Journal · 36

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Initiation and maintenance of pluripotency gene expression in the absence of cohesin

2015 · Thais Lavagnolli, Preksha Gupta, et al. · Genes & Development · 33

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Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming

2016 · Irene Cantone, Hakan Bagci, et al. · Nature Communications · 30

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Estrogen enforces the integrity of blood vessels in the bone during pregnancy and menopause

2022 · Julia Rodrigues, Yi-Fang Wang, et al. · Nature Cardiovascular Research · 29

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STATegra, a comprehensive multi-omics dataset of B-cell differentiation in mouse

2019 · David Gomez-Cabrero, Sonia Tarazona, et al. · Scientific Data · 29

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Galectin-3 activates spinal microglia to induce inflammatory nociception in wild type but not in mice modelling Alzheimer’s disease

2023 · George Sideris-Lampretsas, Silvia Oggero, et al. · Nature Communications · 26

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XPO7 is a tumor suppressor regulating p21CIP1-dependent senescence

2021 · Andrew J. Innes, Bin Sun, et al. · Genes & Development · 26

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A community-based resource for automatic exome variant-calling and annotation in Mendelian disorders

2014 · Margherita Mutarelli, Veer Singh Marwah, et al. · BMC Genomics · 24

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MicroRNAs of the miR-290–295 Family Maintain Bivalency in Mouse Embryonic Stem Cells

2016 · Bryony Graham, Antoine Marcais, et al. · Stem Cell Reports · 22

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Selective deployment of transcription factor paralogs with submaximal strength facilitates gene regulation in the immune system

2019 · Ludovica Bruno, Vijendra Ramlall, et al. · Nature Immunology · 21

Works count: 46

Citation count: 5,153

H-index: 23

I10-index: 29