Work

Selective deployment of transcription factor paralogs with submaximal strength facilitates gene regulation in the immune system

Year: 2019

Type: article

Source: Nature Immunology

DOI: 10.1038/s41590-019-0471-5

Authors: Ludovica Bruno, Vijendra Ramlall, Romain A. Studer, Stephan Sauer, David Bradley, Gopuraja Dharmalingam, Thomas Carroll, Mohamed Ghoneim, Michaël Chopin, Stephen L. Nutt, Sarah Elderkin, David S. Rueda, Amanda G. Fisher, Trevor Siggers, Pedro Beltrao, Matthias Merkenschlager

Institutions: MRC London Institute of Medical Sciences, Medical Research Council, Boston University, European Bioinformatics Institute, BenevolentAI (United Kingdom), Imperial College London, Walter and Eliza Hall Institute of Medical Research, The University of Melbourne, Babraham Institute

Language: English

Topic: Genomics and Chromatin Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: Wellcome Trust, Medical Research Council, Biotechnology and Biological Sciences Research Council, National Institute of Allergy and Infectious Diseases

Awards: Computational systems biology of ageing in haematopoiesis and the immune system, Genomic and epigenomic analysis of ageing in haematopoiesis and the immune system., Genetic approaches to dissect the role of cohesin in gene regulation., Gene Regulation in the Immune System, Genetic approaches to dissect the role of cohesin in gene regulation.

OpenAlex ID: W2970069540

FWCI: 0.879

Cites: 69

Cited by: 21

Related to: 10