Get started
Author

Dan Donnelly

Glucagon-Like Peptide-1 and Its Class B G Protein–Coupled Receptors: A Long March to Therapeutic Successes
2016 · Chris de Graaf, Dan Donnelly, et al. · Pharmacological Reviews · 403
PDF
Environment‐specific amino acid substitution tables: Tertiary templates and prediction of protein folds
1992 · John Overington, Dan Donnelly, et al. · Protein Science · 304
PDF
The structure and function of the glucagon‐like peptide‐1 receptor and its ligands
2011 · Dan Donnelly · British Journal of Pharmacology · 292
Modeling α‐helical transmembrane domains: The calculation and use of substitution tables for lipid‐facing residues
1993 · Tom L. Blundell, Dan Donnelly, et al. · Protein Science · 148
PDF
A three-dimensional model of the Photosystem II reaction centre of Pisum sativum
1992 · Stuart V. Ruffle, Dan Donnelly, et al. · Photosynthesis Research · 136
The Conformational Change Responsible for AT1 Receptor Activation Is Dependent upon Two Juxtaposed Asparagine Residues on Transmembrane Helices III and VII
1997 · Anthony J. Balmforth, Alison J. Lee, et al. · Journal of Biological Chemistry · 107
The Isolated N-terminal Domain of the Glucagon-like Peptide-1 (GLP-1) Receptor Binds Exendin Peptides with Much Higher Affinity than GLP-1
2003 · Rakel López de Maturana, Angela Willshaw, et al. · Journal of Biological Chemistry · 103
PDF
A model for receptor–peptide binding at the glucagon‐like peptide‐1 (GLP‐1) receptor through the analysis of truncated ligands and receptors
2003 · Suleiman Al‐Sabah, Dan Donnelly · British Journal of Pharmacology · 100
PDF
The evolution and structure of aminergic G protein-coupled receptors.
1994 · D Donnelly, J B Findlay, et al. · PubMed · 97
The arrangement of the transmembrane helices in the secretin receptor family of G‐protein‐coupled receptors
1997 · Dan Donnelly · FEBS Letters · 75
PDF
The prediction and orientation of α-helices from sequence alignments: the combined use of environment-dependent substitution tables, Fourier transform methods and helix capping rules
1994 · Dan Donnelly, John P. Overington, et al. · Protein Engineering Design and Selection · 67
Functional expression of glucose-dependent insulinotropic polypeptide receptors is coupled to differentiation in a human adipocyte model
2008 · R E Weaver, D Donnelly, et al. · International Journal of Obesity · 63
The ligand binding site of the neurokinin 2 receptor. Site-directed mutagenesis and identification of neurokinin A binding residues in the human neurokinin 2 receptor.
1994 · N Bhogal, D Donnelly, et al. · Journal of Biological Chemistry · 61
Seven-helix receptors: structure and modelling
1994 · Dan Donnelly, John B.C. Findlay · Current Opinion in Structural Biology · 61
The glucagon‐like peptide‐1 receptor binding site for the N‐terminus of GLP‐1 requires polarity at Asp198 rather than negative charge
2002 · Rakel López de Maturana, Dan Donnelly · FEBS Letters · 60
An analysis of the periodicity of conserved residues in sequence alignments of G‐protein coupled receptors
1989 · D. Donnelly, M.S. Johnson, et al. · FEBS Letters · 59
The GIP Receptor Displays Higher Basal Activity than the GLP-1 Receptor but Does Not Recruit GRK2 or Arrestin3 Effectively
2014 · Suleiman Al-Sabah, Munya Al-Fulaij, et al. · PLoS ONE · 54
PDF
Conserved polar residues in the transmembrane domain of the human tachykinin NK2 receptor: functional roles and structural implications
1999 · Dan DONNELLY, Stuart MAUDSLEY, et al. · Biochemical Journal · 54
PDF
Peptide binding at the GLP-1 receptor
2007 · R. Mann, N. Nasr, et al. · Biochemical Society Transactions · 50
The positive charge at Lys‐288 of the glucagon‐like peptide‐1 (GLP‐1) receptor is important for binding the N‐terminus of peptide agonists
2003 · Suleiman Al-Sabah, Dan Donnelly · FEBS Letters · 41
PDF
Non-peptidic antagonists of the CGRP receptor, BIBN4096BS and MK-0974, interact with the calcitonin receptor-like receptor via methionine-42 and RAMP1 via tryptophan-74
2009 · Philip S. Miller, James Barwell, et al. · Biochemical and Biophysical Research Communications · 40
PDF
Met-204 And Tyr-205 Are Together Important For Binding Glp-1 Receptor Agonists But Not Their N-Terminally Truncated Analogues
2004 · Rakel de Maturana, Janet Treece-Birch, et al. · Protein and Peptide Letters · 40
The peptide agonist-binding site of the glucagon-like peptide-1 (GLP-1) receptor based on site-directed mutagenesis and knowledge-based modelling
2015 · Rachel L. Dods, Dan Donnelly · Bioscience Reports · 36
PDF
The major determinant of exendin‐4/glucagon‐like peptide 1 differential affinity at the rat glucagon‐like peptide 1 receptor N‐terminal domain is a hydrogen bond from SER‐32 of exendin‐4
2010 · RJ Mann, NE Nasr, et al. · British Journal of Pharmacology · 35
PDF
Interactions of the Melanocortin-4 Receptor with the Peptide Agonist NDP-MSH
2010 · Kathryn L. Chapman, Gemma K. Kinsella, et al. · Journal of Molecular Biology · 24
PDF
Works count: 56
Citation count: 2,719
H-index: 24
I10-index: 36
Year
Topic
Type