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Kathleen Quirk

Observed names: K Quirk, K. QUIRK, K. Quirk, KATHLEEN QUIRK
OpenAlex ID: A5113640918
Pharmacological characterisation of the agonist radioligand binding site of 5-HT2A, 5-HT2B and 5-HT2C receptors
2004 · AntonyR. Knight, Anil Misra, et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 248
GABAA receptor subtypes immunopurified from rat brain with α subunit-specific antibodies have unique pharmacological properties
1991 · Ruth M. McKernan, Kathleen Quirk, et al. · Neuron · 196
[ 3 H]L-655,708, a Novel Ligand Selective for the Benzodiazepine Site of GABA A Receptors which Contain the α5 Subunit
1996 · K. QUIRK, P. BLURTON, et al. · Neuropharmacology · 178
A novel allosteric modulatory site on the GABAA receptor β subunit
1994 · K.A. Wafford, C.J. Bain, et al. · Neuron · 174
Model of subunit composition of gamma-aminobutyric acid A receptor subtypes expressed in rat cerebellum with respect to their alpha and gamma/delta subunits.
1994 · K. Quirk, N.P. Gillard, et al. · Journal of Biological Chemistry · 115
3-Heteroaryl-2-pyridones: Benzodiazepine Site Ligands with Functional Selectivity for α2/α3-Subtypes of Human GABAA Receptor-Ion Channels
2002 · Ian Collins, Christopher Moyes, et al. · Journal of Medicinal Chemistry · 110
Rat and Human Hippocampal α5 Subunit-Containing γ-Aminobutyric AcidA Receptors Have α5β3γ2 Pharmaco logical Characteristics
1998 · Cyrille Sur, Kathleen Quirk, et al. · Molecular Pharmacology · 103
Characterisation of δ-subunit containing GABAA receptors from rat brain
1995 · Kathleen Quirk, Paul J. Whiting, et al. · European Journal of Pharmacology Molecular Pharmacology · 92
gamma-Aminobutyric acid type A receptors in the rat brain can contain both gamma 2 and gamma 3 subunits, but gamma 1 does not exist in combination with another gamma subunit.
1994 · K Quirk, N P Gillard, et al. · Molecular Pharmacology · 69
Stable expression of mammalian type A gamma-aminobutyric acid receptors in mouse cells: demonstration of functional assembly of benzodiazepine-responsive sites.
1992 · K L Hadingham, P C Harkness, et al. · Proceedings of the National Academy of Sciences · 66
7-(1,1-Dimethylethyl)-6-(2-ethyl-2 H -1,2,4- triazol-3-ylmethoxy)-3-(2-fluorophenyl)- 1,2,4-triazolo[4,3- b ]pyridazine: A Functionally Selective γ-Aminobutyric Acid A (GABA A ) α2/α3-Subtype Selective Agonist That Exhibits Potent Anxiolytic Activity but Is Not Sedating in Animal Models
2005 · Robert W. Carling, Andrew Madin, et al. · Journal of Medicinal Chemistry · 56
The Pharmacology of the Benzodiazepine Site of the GABA-A Receptor is Dependent on the Type of γ-Subunit Present
1995 · R. M. McKernan, K. Wafford, et al. · Journal of Receptors and Signal Transduction · 53
Indoline derivatives as 5-HT 2C receptor agonists
2004 · J.M Bentley, D.R Adams, et al. · Bioorganic & Medicinal Chemistry Letters · 45
Photoaffinity Labeling of the Benzodiazepine Binding Site of α1β3γ2 γ-Aminobutyric AcidA Receptors with Flunitrazepam Identifies a Subset of Ligands that Interact Directly with His102 of the α Subunit and Predicts Orientation of These within the Benzodiazepine Pharmacophore
1998 · Ruth M. McKernan, Sophie Farrar, et al. · Molecular Pharmacology · 41
Effects of L-690,488, a prodrug of the bisphosphonate inositol monophosphatase inhibitor L-690,330, on phosphatidylinositol cycle markers.
1994 · J R Atack, A M Prior, et al. · Journal of Pharmacology and Experimental Therapeutics · 36
Purification of the 5-hydroxytryptamine 5-HT3 receptor from NCB20 cells.
1990 · R.M. McKernan, N.P. Gillard, et al. · Journal of Biological Chemistry · 33
Pyrrolo(iso)quinoline derivatives as 5-HT2C receptor agonists
2005 · David R. Adams, Jonathan M. Bentley, et al. · Bioorganic & Medicinal Chemistry Letters · 28
Characterisation of agonist binding on human 5-HT2C receptor isoforms
2001 · Kathleen Quirk, Anthony Lawrence, et al. · European Journal of Pharmacology · 24
Molecular size of the 5-HT3 receptor solubilized from NCB 20 cells
1990 · R M McKernan, C S Biggs, et al. · Biochemical Journal · 20
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Solubilisation of the 5‐Hydroxytryptamine3 Receptor from Pooled Rat Cortical and Hippocampal Membranes
1990 · Ruth M. McKernan, K. Quirk, et al. · Journal of Neurochemistry · 19
N-(Indol-3-ylglyoxylyl)piperidines: high affinity agonists of human GABA-A receptors containing the α1 subunit
2000 · Ian Collins, William B Davey, et al. · Bioorganic & Medicinal Chemistry Letters · 18
Solubilisation and immunoprecipitation of rat striatal adenosine A2A receptors
2001 · Victoria Harvey, Julie Jones, et al. · European Journal of Pharmacology · 9
Mechanisms of G protein activation via the D2 dopamine receptor: evidence for persistent receptor/G protein interaction after agonist stimulation
2007 · K Quirk, D J Roberts, et al. · British Journal of Pharmacology · 6
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Characterization of the solubilized NMDA receptor complex from rat brain with [3H]L-689,560, a glycine site antagonist
1994 · Kathleen Quirk, Alan C. Foster, et al. · Molecular Membrane Biology · 4
90 Characterisation of an HCV NS3/NS4A proteinase fusion protein expressed in E.coli using synthetic peptide substrates
1997 · TREVOR C.I. WILKINSON, PETER R. BUNYARD, et al. · Biochemical Society Transactions · 3
Works count: 27
Citation count: 1,748
H-index: 19
I10-index: 21
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