7-(1,1-Dimethylethyl)-6-(2-ethyl-2 H -1,2,4- triazol-3-ylmethoxy)-3-(2-fluorophenyl)- 1,2,4-triazolo[4,3- b ]pyridazine: A Functionally Selective γ-Aminobutyric Acid A (GABA A ) α2/α3-Subtype Selective Agonist That Exhibits Potent Anxiolytic Activity but Is Not Sedating in Animal Models
Year: 2005
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/jm058034a
Authors: Robert W. Carling, Andrew Madin, Alec Guiblin, Michael G. N. Russell, Kevin W. Moore, Andrew Mitchinson, Bindi Sohal, Andrew Pike, Susan M. Cook, Ian C. Ragan, Ruth M. McKernan, Kathleen Quirk, Pushpinder Ferris, George Marshall, Sally Ann Thompson, Keith A. Wafford, Gerard R. Dawson, John R. Atack, Timothy Harrison, José L. Castro, Leslie J. Street
Institution: MSD (UK) Limited (United Kingdom)
Language: English
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: closed
OpenAlex ID: W2016940189
