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81125023

Funded outputs count: 49
Funder award ID: 81125023
OpenAlex ID: G5180304169
Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis
2021 · Ying Dong, Bi-xi Tang, et al. · Acta Pharmacologica Sinica · 20
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Roxithromycin attenuates bleomycin-induced pulmonary fibrosis by targeting senescent cells
2021 · Xuan Zhang, Ying Dong, et al. · Acta Pharmacologica Sinica · 57
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Discovery and Optimization of Non-bile Acid FXR Agonists as Preclinical Candidates for the Treatment of Nonalcoholic Steatohepatitis
2020 · Junyou Li, Mengqi Liu, et al. · Journal of Medicinal Chemistry · 38
Design and synthesis of new lenalidomide analogs via Suzuki cross‐coupling reaction
2020 · Donghuai Xiao, Yu‐jie Wang, et al. · Archiv der Pharmazie · 17
Discovery of a 2-pyridinyl urea-containing compound YD57 as a potent inhibitor of apoptosis signal-regulating kinase 1 (ASK1)
2020 · Shiyan Zhang, Chaoying Huang, et al. · European Journal of Medicinal Chemistry · 13
Discovery of a Potent and Selective NF-κB-Inducing Kinase (NIK) Inhibitor That Has Anti-inflammatory Effects in Vitro and in Vivo
2020 · Zhiqiang Li, Xinzhi Li, et al. · Journal of Medicinal Chemistry · 43
Identification and structural insight of an effective PPARγ modulator with improved therapeutic index for anti-diabetic drug discovery
2020 · Haowen Jiang, X. Edward Zhou, et al. · Chemical Science · 36
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A fluorogenic probe for tracking GSH flux in developing neurons
2019 · Haichao Zong, Jiayi Peng, et al. · Chemical Communications · 26
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Berberine promotes the recruitment and activation of brown adipose tissue in mice and humans
2019 · Lingyan Wu, Mingfeng Xia, et al. · Cell Death and Disease · 138
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Self-Assembled 2D Glycoclusters for the Targeted Delivery of Theranostic Agents to Triple-Negative Breast Cancer Cells
2019 · Xi-Le Hu, Quanyu Cai, et al. · ACS Applied Materials & Interfaces · 20
Self-Assembled Thin-Layer Glycomaterials With a Proper Shell Thickness for Targeted and Activatable Cell Imaging
2019 · Chao Zhang, Guanzhen Wang, et al. · Frontiers in Chemistry · 1
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Sensors, Imaging Agents, and Theranostics to Help Understand and Treat Reactive Oxygen Species Related Diseases
2019 · Kai‐Cheng Yan, Adam C. Sedgwick, et al. · Small Methods · 88
SIRT5 Regulates Brown Adipocyte Differentiation and Browning of Subcutaneous White Adipose Tissue
2019 · Lin Shuai, Li-Na Zhang, et al. · Diabetes · 63
Synthesis and biological evaluation of tryptophan-derived rhodanine derivatives as PTP1B inhibitors and anti-bacterial agents
2019 · Hongyan Liu, Danwen Sun, et al. · European Journal of Medicinal Chemistry · 34
New sesquiterpenoids from the South China Sea soft corals Clavularia viridis and Lemnalia flava
2019 · Qihao Wu, Yuan Gao, et al. · Beilstein Journal of Organic Chemistry · 11
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Post-translational regulation of lipogenesis via AMPK-dependent phosphorylation of insulin-induced gene
2019 · Yamei Han, Zhimin Hu, et al. · Nature Communications · 157
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Benzo[c][1,2,5]thiadiazole derivatives: A new class of potent Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors
2017 · Wen-Long Wang, Xiao-Yu Chen, et al. · Bioorganic & Medicinal Chemistry Letters · 33
Metabolic Regulation of Gene Expression by Histone Lysine β‐hydroxybutyrylation
2017 · Di Zhang, Zhongyu Xie, et al. · The FASEB Journal · 3
Metabolic Regulation of Gene Expression by Histone Lysine β-Hydroxybutyrylation
2016 · Zhongyu Xie, Di Zhang, et al. · Molecular Cell · 779
A new and efficient ZnCl2-catalyzed synthesis and biological evaluation of novel 2-amino-3,5-dicyano-4-aryl-6-aryl-aminopyridines as potent antibacterial agents against Helicobacter pylori (HP)
2015 · Jijun Huang, Jie Zhou, et al. · Tetrahedron · 17
Design, synthesis and biological evaluation of isoquinoline-based derivatives as novel histone deacetylase inhibitors
2015 · Wei Yang, Lixuan Li, et al. · Bioorganic & Medicinal Chemistry · 20
Synthesis of Novel 3‐aryl‐1‐oxa‐2,8‐diazaspiro[4.5]dec‐2‐ene Derivatives and Their Biological Evaluation Against Protein Tyrosine Phosphatase 1B
2015 · Wen‐Long Wang, Xia Chen, et al. · Chemical Biology & Drug Design · 10
Functional Role of Histidine in the Conserved His-x-Asp Motif in the Catalytic Core of Protein Kinases
2015 · Lun Zhang, Jian-Chuan Wang, et al. · Scientific Reports · 28
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PTP1B inhibitors from stems of Angelica keiskei (Ashitaba)
2015 · Jin-long Li, Li-xin Gao, et al. · Bioorganic & Medicinal Chemistry Letters · 32
Physalin B not only inhibits the ubiquitin-proteasome pathway but also induces incomplete autophagic response in human colon cancer cells in vitro
2015 · Yi-ming Ma, Wei Han, et al. · Acta Pharmacologica Sinica · 31