Work

Discovery and Optimization of Non-bile Acid FXR Agonists as Preclinical Candidates for the Treatment of Nonalcoholic Steatohepatitis

Year: 2020

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.0c01065

Authors: Junyou Li, Mengqi Liu, Yazhou Li, Dan-dan Sun, Zhihao Shu, Qian Tan, Shimeng Guo, Rongrong Xie, Lixin Gao, Hongbo Ru, Yi Zang, Hong Liu, Jia Li, Yu Zhou

Institutions: Chinese Academy of Sciences, Shanghai Institute of Materia Medica, Qingdao National Laboratory for Marine Science and Technology, University of Chinese Academy of Sciences, State Key Laboratory of Drug Research, Nanjing University of Chinese Medicine

Language: English

Topic: Liver Disease Diagnosis and Treatment

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Ministry of Science and Technology of the People's Republic of China, K. C. Wong Education Foundation

Awards: 基于代谢型谷氨酸受体负变构调节剂的发现及其抗抑郁活性研究, G149765585, G5180304169, G6846714587, G7174992579

OpenAlex ID: W3090469866

FWCI: 1.469

Cites: 56

Cited by: 38

Related to: 10