Work

In Vivo Activities of Recombinant Divercin V41 and Its Structural Variants against Listeria monocytogenes

Year: 2009

Type: article

Abstract: Recombinant divercin RV41 (DvnRV41) and its structural variants were used in this study to assess their antilisterial activities in vivo in mice challenged intravenously with Listeria monocytogenes EGDe. Treatment with DvnRV41 before and after infection permitted a conclusion as to the capacities of this peptide to retain activity and reduce growth of L. monocytogenes EGDe. Moreover, the use of structural variants for the first time in vivo and the reductions of their activities confirmed the importance of certain amino acids in antilisterial activity.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.00765-09

Authors: Jitka Rihakova, Jean-Michel Cappelier, Isabelle Hue, Katerina Demnerova, Michel Fédérighi, Hervé Prévost, Djamel Drider

Institutions: SECurité des ALIments et Microbiologie, École Nationale d'Ingénieurs des Techniques des Industries Agro-Alimentaires

Language: English

Topic: Antimicrobial Peptides and Activities

Subfield: Microbiology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W1977409592

FWCI: 2.278

Cites: 17

Cited by: 29

Related to: 10