Work

xCT Inhibition Depletes CD44v-Expressing Tumor Cells That Are Resistant to EGFR-Targeted Therapy in Head and Neck Squamous Cell Carcinoma

Year: 2013

Type: article

Source: Cancer Research

DOI: 10.1158/0008-5472.can-12-3609-t

Authors: Momoko Yoshikawa, Kenji Tsuchihashi, Takatsugu Ishimoto, Toshifumi Yae, Takeshi Motohara, Eiji Sugihara, Nobuyuki Onishi, Takashi Masuko, Kunio Yoshizawa, Shuichi Kawashiri, Makio Mukai, Seiji Asoda, Hiromasa Kawana, Taneaki Nakagawa, Hideyuki Saya, Osamu Nagano

Institutions: Kanazawa University, Keio University, Japan Science and Technology Agency, Keio University Hospital, Kindai University

Language: English

Topic: Cancer, Hypoxia, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funder: Japan Society for the Promotion of Science

Awards: Elucidation of chronic periodontitis tissue destruction and tissue remodeling mechanism as seen from the periodontal tissue stem cells, Analysis of CD44 role in metabolism of leukemic stem cell, Suppressive effect of invasion and metastasis of oral squamous cell carcinoma by Claudin expression, New classification of oral squamous cell carcinoma based on the molecular expression profile controlling the epithelial mesenchymal transition and stem cell-like characteristics, The identification of functional role of CD44 in redox status and the application to therapeutic strategy in cancer

OpenAlex ID: W1980932672

FWCI: 5.907

Cites: 41

Cited by: 191

Related to: 10