Imidazoquinoxaline Src-Family Kinase p56Lck Inhibitors: SAR, QSAR, and the Discovery of (S)-N-(2-Chloro-6-methylphenyl)-2-(3-methyl-1-piperazinyl)imidazo- [1,5-a]pyrido[3,2-e]pyrazin-6-amine (BMS-279700) as a Potent and Orally Active Inhibitor with Excellent in Vivo Antiinflammatory Activity
Year: 2004
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/jm030217e
Authors: Ping Chen, Arthur M. Doweyko, Derek Norris, Henry H. Gu, Steven H. Spergel, Jagabundhu Das, Robert V. Moquin, James Lin, John Wityak, Edwin J. Iwanowicz, Kim W. McIntyre, David J. Shuster, Kamelia Behnia, Saeho Chong, Henry de Fex, Suhong Pang, Sydney Pitt, Ding Ren Shen, Sara Thrall, Paul Stanley, Octavian R. Kocy, Mark R. Witmer, Steven B. Kanner, Gary L. Schieven, Joel C. Barrish
Institution: Bristol-Myers Squibb (United States)
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: closed
OpenAlex ID: W2085122016