Work

Synthesis of 2,3-Disubstituted Indole Using Palladium(II)-Catalyzed Cyclization with Alkenylation Reaction.

Year: 2002

Type: article

Abstract: The reaction of ethyl 2-ethynylphenylcarbamate derivative with alkenes in the presence of a palladium(II) catalyst, copper dichloride and tetrabutylammonium fluoride (TBAF) produced 2-substituted 3-ethenylindoles during refluxing. The intramolecular cyclization reaction of ethyl 2-ethynylphenylcarbamates, which have an ethenyl part in the ethynyl group, was also used to produce carbazole derivatives.

Source: Chemical and Pharmaceutical Bulletin

DOI: 10.1248/cpb.50.235

Authors: Akito Yasuhara, Yousuke Takeda, Naoyuki Suzuki, Takao Sakamoto

Institution: Tohoku University

Language: English

Topic: Synthesis of Indole Derivatives

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

OpenAlex ID: W2153138704

FWCI: 2.109

Cites: 9

Cited by: 57

Related to: 10