Work

Identification of selective inhibitors of sphingosine kinases 1 and 2 through a structure–activity relationship study of 4-epi-jaspine B

Year: 2017

Type: article

Source: Bioorganic & Medicinal Chemistry

DOI: 10.1016/j.bmc.2017.03.059

Authors: Hiroaki Ohno, Maho Honda, Naoka Hamada, Jun Miyagaki, Akira Iwata, Kazuhiro Otsuki, Toru Maruyama, Shinya Nakamura, Isao Nakanishi, Shinsuke Inuki, Nobutaka Fujii, Shinya Oishi

Institutions: Kyoto University, Ono Pharmaceutical (Japan), Kindai University, Keio University

Language: English

Topic: Sphingolipid Metabolism and Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

Funders: Uehara Memorial Foundation, Ministry of Education, Culture, Sports, Science and Technology, Japan Society for the Promotion of Science

Awards: Development of Novel Drug Discovery Technologies for Target Proteins with Elusive Molecular Basis, Precise activation based on transition state control using neighboring effect and its medicinal application, Synthetic and medicinal studies on bioactive indole alkaloids based on direct construction of polycyclic ring systems, G4646237965, G5711480817, Innovative Molecular Transformations Based on Consecutive pai-Activation and Their Medicinal Applications

OpenAlex ID: W2603773643

FWCI: 0.585

Cites: 51

Cited by: 13

Related to: 10