Work

Discovery of a lead series of potent benzodiazepine 5-HT2C receptor agonists with high selectivity in functional and binding assays

Year: 2019

Type: article

Source: Bioorganic & Medicinal Chemistry Letters

DOI: 10.1016/j.bmcl.2019.126929

Authors: Albert Ren, Xiuwen Zhu, Konrad Feichtinger, Juerg Lehman, Michelle Kasem, Thomas O. Schrader, Amy Wong, Huong Dang, Minh Le, John Frazer, David J. Unett, Andrew J. Grottick, Kevin T. Whelan, Michael E. Morgan, Carleton R. Sage, Graeme Semple

Institution: Arena Pharmaceuticals (United States)

Language: English

Topic: Synthesis and pharmacology of benzodiazepine derivatives

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W2997754277

FWCI: 0.373

Cites: 24

Cited by: 6

Related to: 10