Work

Discovery of Clinical Candidate NT-0796, a Brain-Penetrant and Highly Potent NLRP3 Inflammasome Inhibitor for Neuroinflammatory Disorders

Year: 2023

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.3c01398

Authors: David Harrison, Andy Billinton, Mark G. Bock, John R. Doedens, Christopher A. Gabel, M. Katharine Holloway, Roderick A. Porter, Valérie Reader, Jane Scanlon, Kenneth Schooley, Alan P. Watt

Language: English

Topic: Inflammasome and immune disorders

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W4387900920

FWCI: 8.253

Cites: 29

Cited by: 93

Related to: 10