Work

Computation-Enabled Structure-Based Discovery of Potent Binders for Small-Molecule Aptamers

Year: 2025

Type: article

Source: Journal of Chemical Theory and Computation

DOI: 10.1021/acs.jctc.4c01246

Authors: Qingtong Zhou, Zheng Zhang, Ling Gao, Guanyi Li, Yue Zhang, Weili Yang, Yaxue Zhao, Dehua Yang, Ming-Wei Wang, Zhaofeng Luo, Xiaole Xia

Institutions: Shanghai Medical College of Fudan University, Shanghai Jiao Tong University, Fudan University, Ruijin Hospital, State Key Laboratory of Medical Genomics, Chinese Academy of Sciences, Hangzhou Institute of Medicine, Chinese Academy of Sciences, Jiangnan University, University of Science and Technology of China, Shanghai Institute of Materia Medica, National Center for Drug Screening, Hainan Medical University, Tianjin University of Science and Technology

Language: English

Topic: Computational Drug Discovery Methods

Subfield: Drug Discovery

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

Open Access status: closed

Funders: National Natural Science Foundation of China, National Key Research and Development Program of China, Project 211, Major Science and Technology Project of Hainan Province, Key Research and Development Program of Zhejiang Province

Awards: G1313489940, G1898721675, G5809980136, G6569680945, G7993491815

OpenAlex ID: W4408102402

FWCI: 0.877

Cites: 78

Cited by: 3

Related to: 10