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Discovery and X-ray Crystallographic Analysis of a Spiropiperidine Iminohydantoin Inhibitor of β-Secretase

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Year: 2008
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/jm800914n
Authors: James C. Barrow, Shaun R. Stauffer, Kenneth E. Rittle, Phung L. Ngo, ZhiQiang Yang, Harold G. Selnick, Samuel L. Graham, Sanjeev Munshi, Georgia B. McGaughey, M. Katharine Holloway, Adam J. Simon, Eric A. Price, Sethu Sankaranarayanan, Dennis Colussi, Katherine Tugusheva, Ming-Tain Lai, Amy S. Espeseth, Min Xu, Qian Huang, Abigail Wolfe, Beth Pietrak, Paul Zuck, Dorothy A. Levorse, Daria Hazuda, Joseph P. Vacca
Language: English

Topic: Alzheimer's disease research and treatments
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: closed
OpenAlex ID: W2242987777
FWCI: 6.095
Cites: 23
Cited by: 60
Related to: 10
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