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KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance

Year: 2018
Type: article
Source: Cancer Cell
DOI: 10.1016/j.ccell.2018.10.014
Authors: Kunihiko Hinohara, Hua-Jun Wu, Sébastien Vigneau, Thomas O. McDonald, Kyomi J. Igarashi, Kimiyo N. Yamamoto, Thomas Madsen, Anne Fassl, Shawn B. Egri, Malvina Papanastasiou, Lina Ding, Guillermo Peluffo, Ofir Cohen, Stephen C. Kales, Madhu Lal-Nag, Ganesha Rai, David J. Maloney, Ajit Jadhav, Anton Simeonov, Nikhil Wagle, Myles Brown, Alexander Meissner, Piotr Sicinski, Jacob D. Jaffe, Rinath Jeselsohn, Alexander A. Gimelbrant, Franziska Michor, Kornelia Polyak
Institutions: Harvard University, Dana-Farber Cancer Institute, Dana-Farber/Harvard Cancer Center, Broad Institute, Massachusetts Institute of Technology, National Center for Advancing Translational Sciences
Language: English
Open Access status: bronze
Awards: G3352250835, G340051698, Novel functions of D-type and E-type cyclins in normal and in cancer cells, There and Back Again: Epigenetic Reinforcement of Cellular Signaling States - Overall, Elucidating and overcoming endocrine resistance driven by ESR1 mutations, G784047723
OpenAlex ID: W2901933835
FWCI: 8.315
Cites: 62
Cited by: 252
Related to: 10