Work

Hemp seed mitigates colonic inflammation through macrophage polarization and microbiota-barrier axis restoration

Year: 2025

Type: article

Abstract: , while suppressing colitis-associated genera. Collectively, these findings indicate that hemp seed, as a whole-food dietary approach, confers protection against colitis by modulating immune responses, preserving barrier integrity, and reshaping gut microbiome. These results underscore the potential of hemp seed as a sustainable nutritional strategy for promoting gut health.

Source: Food & Function

DOI: 10.1039/d5fo04119h

Authors: Jieun Woo, Dekun Cheng, Erica A. Long, Kristin L. Whitney, Guangyi Shen, Lavanya Reddivari, Qing Jiang, Senay Simsek, Tingting Ju, Weicang Wang

Institution: Purdue University West Lafayette

Language: English

Topic: Gut microbiota and health

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDGs: Good health and well-being, Zero hunger

Open Access status: hybrid

Funders: U.S. Department of Agriculture, Purdue University, Ralph W. and Grace M. Showalter Research Trust Fund, National Institute of Food and Agriculture

Awards: G1057676700, G3949791526

OpenAlex ID: W4416946884

FWCI: 0.783

Cites: 53

Cited by: 3

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