Rectal Acquisition of Simian Immunodeficiency Virus (SIV) SIVmac239 Infection despite Vaccine-Induced Immune Responses against the Entire SIV Proteome
Year: 2020
Type: article
Abstract: Our results are relevant to HIV vaccine development efforts because they suggest that increasing the number of booster immunizations or delivering additional viral antigens may not necessarily improve vaccine efficacy against immunodeficiency virus infection.
Source: Journal of Virology
DOI: 10.1128/jvi.00979-20
Authors: Mauricio A. Martins, Lucas Gonzalez-Nieto, Michael J. Ricciardi, Varian K. Bailey, Christine M. Dang, Georg F. Bischof, Nuria Pedreño-Lopez, Matthias G. Pauthner, Dennis R. Burton, Christopher L. Parks, Patricia Earl, Bernard Moss, Eva G. Rakasz, Jeffrey D. Lifson, Ronald C. Desrosiers, David I. Watkins
Institutions: University of Miami, Scripps Research Institute, International AIDS Vaccine Initiative, National Institutes of Health, National Institute of Allergy and Infectious Diseases, University of Wisconsin–Madison, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc. (United States)
Language: English
Topic: HIV Research and Treatment
Subfield: Virology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
Awards: G2399437601, Can vaccine-induced CD8 T cells prevent chronic phase AIDS virus replication?, Ipilimumab as an adjuvant for HIV vaccines, G386607036, The Functional Significance of CTL Escape, G5888954722, Gamma-2 Herpesviruses as Vaccine Vectors for AIDS, Wisconsin National Primate Research Center Support, Miami Center for AIDS Research
OpenAlex ID: W3092016126